Prof. Dr. Monika Stengl

Professur für Tierphysiologie

Anschrift Heinr.-Plett-Straße 40
34132 Kassel
Gebäude: AVZ2

Raum 2184

Telefon +49 561 804-4564
Telefax +49 561 804-4146
E-Mail-Adresse stengl@uni-kassel.de

Bild von Prof. Dr. Monika  Stengl


Die Arbeiten der AG Stengl befassen sich mit der olfaktorischen Transduktion beim Tabakschwärmer Manduca sexta und der Charakterisierung der Kopplungsmechanismen der Inneren Uhr bei der Schabe Rhyparobia maderae und der Fruchtfliege Drosophila melanogaster.


Sprechzeiten Fr. Prof. Dr. Monika Stengl

Dienstags von 11.00 bis 12.00 Uhr sowie in der vorlesungsfreien Zeit nach Vereinbarung


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Publikationen

Rojas P, Gestrich J, Plath J, Ananthasubramaniam B, Garcia ME, Herzel HP, Stengl M (2019) Beyond spikes - multiscale computational analysis of in vivo long-term recordings in the cockroach circadian clock. Network Neurosci in press

Fandino RA, Haverkamp A, Bisch-Knaden S., Zhang J, Bucks S, Schröder K, Thi T-A N, Werckethin A, Ryback J, Stengl M, Knaden M, Hansson BS, Große-Wilde E (2019) Mutagenesis of odorant co-receptor Orco fully disrupts foraging but not oviposition behaviors in the hawkmoth Manduca sexta, PNAS 116(31):15677-15685

Giese M, Wei HY, Stengl M (2018) Circadian pacemaker neurons of the Madeira cockroach are inhibited and activated by GABAA and also by GABAB receptors. Eur J Neurosci . doi: 10.1111/ejn.14268. [Epub ahead of print]

Gawalek P, Stengl M (2018) The diacylglycerol analogues OAG and DOG differentially affect primary events of pheromone transduction in the hawkmoth Manduca sexta in a Zeitgebertime-dependent manner apparently targeting TRP channels.

Giese M, Gestrich J, Massah A, Peterle J, Wei HY, Stengl M (2018) GABA- und serotonin-expressing neurons take part in inhibitory as well as excitatory input pathways to the circadian clock of the Madeira cockroach Rhyparobia maderae. Eur J Neurosci May;47(9):1067-1080. doi: 10.1111/ejn.13863. Epub 2018 Feb 27. PMID: 29430734

Gestrich J, Giese M, Shen W, Zhang Y, Voss A, Popov C, Stengl M, Wei HY (2018) Sensitivity to pigment-dispersing factor (PDF) is cell-type specific among PDF-expressing circadian clock neurons in the Madeira cockroach. J Biol Rhythms, Feb;33(1):35-51. doi: 10.1177/0748730417739471. Epub 2017 Nov 28. PMID: 29179611

Wicher D, Morinaga S, Halty-deLeon L, Funk N, Hansson B, Touhara K, Stengl M (2017) Identification and characterization of the bombykal receptor in the hawkmoth Manduca sexta. J Exp Biol 220(10): 1781-1786.

Arendt A, Baz ES, Stengl M (2017) Functions of corazonin and histamine in light entrainment of the circadian pacemaker in the Madeira cockroach, Rhyparobia maderae. J Comp Neurol 525(5): 1250-1272.

Klinner, CF, König C, Missbach C, Werckenthin A, Daly KC, Bisch-Knaden S, Stengl M, Hansson BS, Große-Wilde E (2016) Functional olfactory sensory neurons housed in olfactory sensilla on the ovipositor of the hawkmoth Manduca sexta. Frontiers in Ecology and Evolution 4: 130- doi: 10.3389/fevo.2016.00130

Nolte A, Gawalek P, Koerte S, Stengl M (2016) No evidence for ionotropic pheromone transduction in the hawkmoth Manduca sexta. PLOS ONE 11(11):e0166060. doi: 10.1371/journal.pone.0166060

Voss A, Wei H, Zhang Y, Turner S, Ceccone G, Reithmaier JP, Stengl M, Popov C (2016) Strong attachment of circadian pacemaker neurons on modified ultrananocrystalline diamond surfaces. Mater Sci Eng C Mater Biol Apl 64:278-2785.

Arendt A, Neupert S, Schendzeilorz J, Predel R, Stengl M (2016) The distribution of SIFamide in three cockroach species. J Comp Neurol 524(7) 1337-1360.

Schenzielorz T, Schirmer K, Stolte P, Stengl M (2015) Octopamine regulates antennal sensory neurons via daytime-dependent changes in cAMP and IP3 levels in the hawkmoth Manduca sexta. PLOS ONE Mar 18;10(3):e0121230. doi: 10.1371/journal.pone.0121230. eCollection 2015.

Wei H, Yasar H, Funk NW, Giese M, Baz E-S, Stengl M (2014) Signaling of pigment-dispersing factor (PDF) in the Madeira cockroach Rhyparobia maderae. PLOS ONE Sep 30; 9(9):e108757. doi: 10.1371/

Schendzielorz J, Schendzielorz T, Arendt A, Stengl M (2014) Bimodal oscillations of cyclic nucleotide concentrations in the circadian system of the Madeira cockroach Rhyparobia maderae. J Biol Rhythms 29(5):318-331

Schendzielorz J, Stengl M (2014) Candidates for the light entrainment pathway to the circadian clock of the Madeira cockroach Rhyparobia maderae. Cell and Tissue Res 355(2):447-462

Schulze J, Schendzielorz T, Neupert S, Predel R, Stengl M (2013) Neuropeptidergic input pathways to the circadian pacemaker center of the Madeira cockroach analyzed with an improved injection technique. Eur J Neurosci 38(6):2842-2852

Nolte A, Funk N, Mukunda L, Gawalek P, Werckenthin A, Hansson BS, Wicher D, Stengl M (2013) In situ tip-recordings found no evidence for an Orco-based ionotropic mechanism of pheromone-transduction in Manduca sexta. PLOS ONE 8(5)e62648.doi PMID: 23671617

Baz E-S, Wei H, Grosshans J, Stengl M (2013) Calcium responses of circadian pacemaker neurons of the cockroach Rhyparobia maderae to acetylcholine and histamine. J Comp Physiol A, 199(5): 365-374

Werckenthin A, Derst C, Stengl (2012) Sequence and expression of per, tim1, and cry2 genes in the Madeira cockroach Rhyparobia maderae J Biol Rhythms 6:453-466

Schendzielorz T, Peters W, Boekhoff I, Stengl M (2012) Time of day changes in cyclic nucleotides are modified via octopamine and pheromone in antennae of the Madeira cockroach. J Biol Rhythms 27(5):388-397

Wei H, Stengl M (2012) Ca2+-dependent ion channels underlying spontaneous activity in insect circadian pacemaker neurons. European J Neurosci 36(8):3021-3029

Voss A, Wei H, Müller C, Popov C, Kulisch W, Ceccone G, Ziegler C, Stengl M, Reithmaier JP (2012) Influence f the surface termination of ultrananocrystalline diamond/amorphous carbon composite films on their interaction with neurons. Diamond and Related Materials 26:60-65

Schulze J, Neupert S, Schmidt L, Predel R, Lamkemeyer T, Homberg U, and Stengl M (2012) Myoinhibitory peptide in the brain of the cockroach Leucophaea maderae and colocalization with pigment-dispersing factor in circadian pacemaker cells.  J Comp Neurol 520(5):1078-1097

Wei H, Stengl M (2011) Light affects the branching pattern of peptidergic circadian pacemaker neurons in the brain of the cockroach Leucophaea maderae. J Biol Rhythms 26(6):507-517

Söhler S, Stengl M, Reischig T (2011) Circadian pacemaker coupling by multi-peptidergic neurons in the cockroach Leucophaea maderae. Cell Tiss Res 343:559-577

Wei H, el Jundi B, Homberg U, Stengl M (2010) Implementation of pigment-dispersing factor-immunoreactive neurons in a standardized atlas of the brain of the cockroach Leucophaea maderae .J Comp Neurol 518(20):4113-43333

Flecke C, Nolte A, Stengl M (2010) Perfusion with cAMP analogue affects pheromone-sensitive trichoid sensilla of the hawkmoth Manduca sexta in a daytime-dependent manner. J Exp Biol 213: 842-852

Flecke C, Stengl M (2009) Octopamine and tyramine sensitize pheromone-sensitive olfactory sensilla of the hawkmoth Manduca sexta in a daytime-dependent manner. J Comp Physiol A 195: J Comp Physiol A 195:529-545

Krannich S, Stengl M (2008) Cyclic nucleotide-activated currents in cultured olfactory receptor neurons of the hawkmoth Manduca sexta. J Neurophysiol, 100:2866-2877

Dolzer J, Krannich S, Stengl M (2008) Pharmacological investigation of protein kinase C and cGMP-dependent ion channels in cultured olfactory receptor neurons of the hawkmoth Manduca sexta. Chem Senses 33:803-813

Söhler S, Neupert S, Predel R, Stengl M (2008) An examination of the role of FMRFamides in the circadian clock of the cockroach Leucophaea maderae. Cell and Tissue Res 332:257-269

Schuckel J, Siwicki KK, Stengl M (2007) Putative circadian pacemaker cells in the antenna of the hawkmoth Manduca sexta. Cell Tissue Res 330(2):271-278

Söhler S, Neupert S, Predel R, Nichols R, Stengl M (2007) Localization of leucomyosuppressin in the brain and the circadian clock of the cockroach Leucophaea maderae. Cell Tissue Res 328(2):443-452

Schneider N-L, Stengl M (2007) Long term recordings of the isolated circadian pacemaker center of the cockroach Leucophaea maderae reveals circadian and ultradian rhtyhms. J Comp Physiol A 193(1):35-42

Flecke C, Dolzer J, Stengl M (2006) Perfusion with cGMP adapts the action potential response in pheromone-dependent trichoid sensilla in the moth Manduca sexta. J Exp Biol  209:3898-3912

Schneider N-L, Stengl M (2006) Gap junctions between accessory medulla neurons appear to synchronize circadian clock cells. J Neurophysiol 95(3):1996-2002

Wicher D, Agricola  H-J, Söhler S, Gundel M, Heinemann, SH, Wollweber L, Stengl M, Derst C. (2006) Differential receptor activation by cockroach adipokinetic hormones produces differential effects on ion currents neuronal activity and locomotion J Neurophysiol 96(2):2314-2325

Schneider N-L, Stengl M (2005) Pigment-dispersing factor and GABA synchronize insect circadian clock cells. J Neurosci, 25:5138-5147

Reischig T, Petri B, Stengl M (2004) Pigment-dispersing hormone-immunoreactive neurons form a direct coupling-pathway between the bilaterally symmetric circadian pacemakers of the cockroach Leucophaea maderae. Cell Tissue Res, 318: 553-64

Reischig T, Stengl M (2003b) Ultrastructure of pigment-dispersing hormone-immunoreactive neurons in a three-dimensional model of the accessory medulla of the cockroach Leucophaea maderae. Cell Tissue Res, 314:421-435

Reischig T, Stengl M (2003a) Ectopic transplantation of the accessory medulla restores circadian locomotor rhythms in arrhythmc cockroaches (Leucophaea maderae). J Exp Biol 206:1877-1886

Dolzer J, Fischer K, Stengl M (2003) Adaptation in pheromone-sensitive trichoid sensilla of the hawkmoth Manduca sexta. J Exp Biol 206:1575-1588

Petri B, Loesel R, Homberg U, Stengl M (2002) Evidence for a role of GABA and Mas-allatotropin in photic entrainment of the circadian clock of the cockroach Leucophaea maderae. J Exp Biol  205:1459-69

Reischig T, Stengl M (2002) Optic lobe commissures in a 3D-brain model of the cockroach Leucophaea maderae: a search for the circadian coupling pathways. J Comp Neurol 443:388-400

Dolzer J, Krannich S, Fischer K, Stengl M (2001) Oscillations of the transepithelial potential of moth olfactory sensilla are influenced by octopamine and serotonin. J Exp Biol 204:2781-2794

Petri B, Stengl M (2001) Phase-response curves of a molecular model oscillator:their implication in mutual coupling of paired oscillators. J Biol Rhythms 6:125-141

Stengl M, Zintl R, de Vente J, Nighorn A (2001) Localization of cGMP-immunoreactivity and of soluble guanylyl cyclase in antennal sensilla of the hawkmoth Manduca sexta. Cell and Tissue Res 304:409-421

Petri B, Stengl M (1999) Presumptive insect circadian pacemakers in vitro: immunocytochemical characterization of cultured pigment-dispersing hormone immunoreactive neurons. Cell Tissue Res 296:635-643

Petri B, Stengl M (1997) Pigment-dispersing hormone phase-shifts the circadian pacemaker of the cockroach Leucophaea maderae. J Neurosci, 17:4087-4093

Reischig T, Stengl M (1996) Light- und electronmicroscopic analysis of the accessory medulla, the presumptive pacemaker center of the cockroach Leucophaea maderae. Cell Tissue Res, 285:305-319

Stengl M, Zintl R (1996) NADPH-diaphorase staining in the antenna of the moth Manduca sexta. J Exp Biol, 199:1063-1072

Petri B, Stengl M, Würden S, Homberg U (1995) Immunocytochemical characterization of the accessory medulla in the cockroach Leucophaea maderae. Cell Tissue Res, 282:3-19

Stengl M (1995) Pigment-dispersing hormone-immunoreactive fibers persist in crickets which remain rhythmic after bilateral transection of the optic stalks. J Comp Physiol A, 176: 217-228

Stengl M, Homberg U (1994) Pigment-dispersing hormone-immunoreactive neurons in the cockroach Leucophaea maderae share properties with circadian pacemaker neurons. J Comp Physiol A, 175:203-213

Stengl M (1994) Inositol-trisphosphate-dependent calcium currents precede cation currents in insect olfactory receptor neurons. J Comp Physiol A, 174:187-194

Stengl M (1993) Intracellular-messenger-mediated cation channels in cultured olfactory receptor neurons. J Exp Biol, 178:125-147

Stengl M, Zufall F, Hatt H, Hildebrand JG (1992) Olfactory receptor neurons from antennae of developing male Manduca sexta respond to components of the species-specific sex pheromone in vitro. J Neurosci, 12:2523-2531

Zufall F, Stengl M, Franke C, Hildebrand JG, Hatt H (1991) Ionic currents of cultured olfactory receptor neurons from antennae of male Manduca sexta. J Neurosci, 11:956-965

Stengl M, Homberg U, Hildebrand JG (1990) Acetylcholinesterase activity in antennal receptor neurons of the sphinx moth Manduca sexta. Cell Tissue Res, 262:245-252

Stengl M, Hildebrand JG (1990) Insect olfactory neurons in vitro: Morphological and immunocytochemical characterization of male-specific antennal receptor cells from developing antennae of male Manduca sexta. J Neurosci, 10: 837-847

Stengl M (1989) Development of an in vitro model system to study primary sensory transduction mechanisms. PhD Thesis, Department of Molecular and Cellular Biology, University of Arizona, Tucson

Reviews/Books

Stengl M (2017) Chemosensory transduction in arthropods. Oxford Handbooks online. The Oxford Handbook of Invertebrate Neurobiology, Ed. John H. Byrne. DOI: 10.1093/oxfordhb/9780190456757.013.15

Stengl M, Arendt A (2016) Peptidergic circadian clock circuits in the Madeira cockroach. Curr Opin Neurobiol. 41: 44-52.

Stengl M, Werckenthin A, Wei HY (2015) How does the circadian clock tick in the Madeira cockroach? Current Opinion Insect Sci, 12:38-45.

Stengl M (2014) Biorhythmen, Kapitel 7.3., Penzlin, Lehrbuch der Tierphysiologie.

Rössler W, Stengl M (2013) Insect chemoreception: a tribute to John G. Hildebrand. J Comp Physiol A 199:875-877

Stengl M, Funk N (2013) The role of Orco in insect odor transduction. J Comp Physiol A., 199:897-909

Stengl M (2010) Pheromone transduction in moths. Frontiers Neurosci Dec 31 4:133

Stengl M (2004) Biorhythmen, Kapitel 7.3., Penzlin, Lehrbuch der Tierphysiologie.

Homberg U, Reischig T, Stengl M (2003) Neural organization of the circadian system of the cockroach Leucophaea maderae. Chronobiology International, 20:577-591

Stengl M (2001) Olfactory information processing in insects: Encoding of signals in the antennal lobe. In: Taddei-Ferretti C, Backhaus W (eds) Series of Biophysics and Byocybernetics. Vol 9. World Scientific, London, pp 569-577

Stengl M (2001) Olfactory information processing in insects: Encoding of chemical signals at the periphery. In: Taddei-Ferretti C, Backhaus W (eds) Series of Biophysics and Biocybernetics. Vol 9. World Scientific, London, Hong Kong, pp 292-298

Stengl M, Ziegelberger G, Boekhoff I, Krieger J (1999) Perireceptor events and transduction mechanisms in insect olfaction. In: Hansson BS (ed) Insect olfaction. Springer, pp 49-66

Helfrich-Förster C, Stengl M, Homberg U (1998) Organization of the circadian system in insects. Chronobiology International 15(6):567-594

Hildebrand JG, Christensen TA, Arbas EA, Hayashi JH, Homberg U, Kanzaki R, Stengl M (1991) Olfaction in Manduca sexta: Cellular mechanisms of responses to sex pheromone. In: Duce IR (ed) Proceedings of NEUROTOX 91. Elsevier, Amsterdam, p 133-143

Stengl M, Hatt H, Breer H (1992) Peripheral processes in insect olfaction. Ann Rev Physiol, 54:665-81

Stengl M (1992) Circadiane Schrittmacher bei Insekten. Futura, 93:25-26

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