Das Team der Entwickungsgenetik
Dr. Katja Kapp
Wissenschaftliche Mitarbeiterin
- Telefon
- +49 561 804-4324
- Fax
- +49 561 804-4057
- k.kapp[at]uni-kassel[dot]de
- Standort
- Heinrich-Plett-Str. 40
34132 Kassel
- Raum
- IBC 1200
- Sprechstunde
Nach Vereinbarung.
Publikationen
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Clemente, G.D., Hannaford, M.R., Beati, S.A.H., Kapp, K., Januschke, J., Griffis, E.R., Müller, H.-A., 2018. Requirement of the Dynein-Adaptor Spindly for Mitotic and Post-Mitotic Functions in Drosophila. Journal of Developmental Biology 6, 9. https://doi.org/10.3390/jdb6020009 https://forschung.uni-kassel.de/converis/portal/detail/Publication/51819986 |
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Spannl, S., Kumichel, A., Hebbar, S., Kapp, K., Gonzalez-Gaitan, M., Winkler, S., Blawid, R., Jessberger, G., Knust, E., 2017. The Crumbs C isoform of Drosophila shows tissue- and stage-specific expression and prevents light-dependent retinal degeneration. Biology Open 6, 165–175. https://doi.org/10.1242/bio.020040 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788576 |
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Kumichel, A., Kapp, K., Knust, E., 2015. A Conserved Di-Basic Motif of Drosophila Crumbs Contributes to Efficient ER Export. Traffic (Copenhagen, Denmark) 16, 604–616. https://doi.org/10.1111/tra.12273 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789061 |
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Kapp, K., Siemens, J., Häring, H.-U., Lammers, R., 2012. Proteolytic processing of the protein tyrosine phosphatase extgreeka extracellular domain is mediated by ADAM17/TACE. European Journal of Cell Biology 91, 687–693. https://doi.org/10.1016/j.ejcb.2012.04.003 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789367 |
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Stjepanovic, G., Kapp, K., Bange, G., Graf, C., Parlitz, R., Wild, K., Mayer, M., Sinning, I., 2011. Lipids trigger a conformational switch that regulates signal recognition particle (SRP)-mediated protein targeting. The Journal of biological chemistry 286, 23489–23497. https://doi.org/10.1074/jbc.M110.212340 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788398 |
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Kilic, A., Klose, S., Dobberstein, B., Knust, E., Kapp, K., 2010. The Drosophila Crumbs signal peptide is unusually long and is a substrate for signal peptide peptidase. European Journal of Cell Biology 89, 449–461. https://doi.org/10.1016/j.ejcb.2010.02.001 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789213 |
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Schrul, B., Kapp, K., Sinning, I., Dobberstein, B., 2010. Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes. The Biochemical journal 427, 523–534. https://doi.org/10.1042/BJ20091005 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788729 |
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Bleyer, A.J., Zivná, M., Hulková, H., Hodanová, K., Vyletal, P., Sikora, J., Zivný, J., Sovová, J., Hart, T.C., Adams, J.N., Elleder, M., Kapp, K., Haws, R., Cornell, L.D., Kmoch, S., Hart, P.S., 2010. Clinical and molecular characterization of a family with a dominant renin gene mutation and response to treatment with fludrocortisone. Clinical nephrology 74, 411–422. https://doi.org/10.5414/CNP74411 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67787882 |
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Kapp, K., Schrempf, S., Lemberg, M.K., Dobberstein, B., 2009. Post-Targeting Functions of Signal Peptides, in: Zimmermann, R. (Hrsg.), Protein Transport into the Endoplasmic Reticulum. CRC Press, London, S. 1–16. https://forschung.uni-kassel.de/converis/portal/detail/Publication/74461071 |
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Zivná, M., Matignon, M., Hodanová, K., Vylet’al, P., Kalbácová, M., Baresová, V., Sikora, J., Blazková, H., Zivný, J., Ivánek, R., Stránecký, V., Sovová, J., Claes, K., Lerut, E., Fryns, J.-P., Hart, P.S., Hart, T., Adams, J., Pawtowski, A., Clemessy, M., Gasc, J.-M., Gübler, M.-C., Antignac, C., Elleder, M., Kapp, K., Grimbert, P., Bleyer, A., Kmoch, S., 2009. Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure. American Journal of Human Genetics 85, 204–213. https://doi.org/10.1016/j.ajhg.2009.07.010 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790871 |
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Dultz, E., Hildenbeutel, M., Martoglio, B., Hochman, J., Dobberstein, B., Kapp, K., 2008. The signal peptide of the mouse mammary tumor virus Rem protein is released from the endoplasmic reticulum membrane and accumulates in nucleoli. The Journal of biological chemistry 283, 9966–9976. https://doi.org/10.1074/jbc.M705712200 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790567 |
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Kapp, K., Siemens, J., Weyrich, P., Schulz, J., Häring, H.-U., Lammers, R., 2007. Extracellular domain splice variants of a transforming protein tyrosine phosphatase alpha mutant differentially activate Src-kinase dependent focus formation. Genes to cells : devoted to molecular {&} cellular mechanisms 12, 63–73. https://doi.org/10.1111/j.1365-2443.2006.01034.x https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789546 |
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Lundin, C., Käll, L., Kreher, S., Kapp, K., Sonnhammer, E., Carlson, J., Heijne, G., Nilsson, I., 2007. Membrane topology of the Drosophila OR83b odorant receptor. FEBS Letters 581, 5601–5604. https://doi.org/10.1016/j.febslet.2007.11.007 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788882 |
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Hennige, A., Stefan, N., Kapp, K., Lehmann, R., Weigert, C., Beck, A., Moeschel, K., Mushack, J., Schleicher, E., Häring, H.-U., 2006. Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20, 1206–1208. https://doi.org/10.1096/fj.05-4635fje https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790415 |
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Weyrich, P., Kapp, K., Niederfellner, G., Melzer, M., Lehmann, R., Häring, H.-U., Lammers, R., 2004. Partitioning-defective protein 6 regulates insulin-dependent glycogen synthesis via atypical protein kinase C. Molecular endocrinology (Baltimore, Md.) 18, 1287–1300. https://doi.org/10.1210/me.2003-0253 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788236 |
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Kapp, K., Knobloch, J., Schüssler, P., Sroka, S., Lammers, R., Kunz, W., Grevelding, C., 2004. The Schistosoma mansoni Src kinase TK3 is expressed in the gonads and likely involved in cytoskeletal organization. Molecular and biochemical parasitology 138, 171–182. https://doi.org/10.1016/j.molbiopara.2004.07.010 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790083 |
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Kapp, K., Coustau, C., Wippersteg, V., Jourdane, J., Kunz, W., Grevelding, C., 2003. Transplantation of in vitro-generated Schistosoma mansoni mother sporocysts into Biomphalaria glabrata. Parasitology Research 91, 482–485. https://doi.org/10.1007/s00436-003-0951-1 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790236 |
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Kapp, K., Metzinger, E., Kellerer, M., Häring, H.-U., Lammers, R., 2003. The protein tyrosine phosphatase alpha modifies insulin secretion in INS-1E cells. Biochemical and biophysical research communications 311, 361–364. https://doi.org/10.1016/j.bbrc.2003.10.011 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789904 |
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Kapp, K., Wippersteg, V., Kunz, W., Jackstadt, W.P., Zahner, H., Grevelding, C., 2002. HSP70-controlled GFP expression in transiently transformed schistosomes☆. Molecular and biochemical parasitology 120, 141–150. https://doi.org/10.1016/S0166-6851(01)00446-7 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67790719 |
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Wippersteg, V., Kapp, K., Kunz, W., Grevelding, C., 2002. Characterisation of the cysteine protease ER60 in transgenic Schistosoma mansoni larvae. International Journal for Parasitology 32, 1219–1224. https://doi.org/10.1016/S0020-7519(02)00092-9 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67788060 |
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Kapp, K., Schüssler, P., Kunz, W., Grevelding, C.G., 2001. Identification, isolation and characterization of a Fyn-like tyrosine kinase from Schistosoma mansoni. Parasitology 122, 317–327. https://doi.org/10.1017/S0031182001007430 https://forschung.uni-kassel.de/converis/portal/detail/Publication/67789725 |