Dr. Sven Fürmeier

Scientific staff of the Chemistry of Mesoscopic Systems

Image: S. Fürmeier
Fürmeier, Sven
Telephone
+49 561 804-4757
Fax
+49 561 804-4752
Email
Site
Chemie mesoskopischer Systeme
Heinrich-Plett-Straße 40
34132 Kassel
Room
AVZ II, 3163

area of re­spons­ib­il­ity

Scientific head of the central laboratory for mass spectrometry. This includes the routine analysis of mass spectrometry, the interpretation of spectra and support in scientific questions. In addition, the organisational work in research, education and administration is carried out within the field of nanostructure sciences or the Institute of Chemistry.

Doc­tor­ate

"Microreactor-coupled electrospray ionization mass spectrometry: a new tool for the investigation of reactive intermediates in solution". Finished in 2004 at the Carl von Ossietzky University Oldenburg. Within the scope of the dissertation, a novel method for the direct detection of reactive intermediates during reactions in solution using microreactor-coupled electrospray ionization mass spectrometry (ESI-MS) was optimized and examined for its general applicability. This further developed method allows the mass spectrometric monitoring of reaction processes via the decrease of educts and the associated increase of products and in particular the investigation of reactive intermediates. Basic reaction types in organic chemistry, such as electron transfer-initiated radical cation chain reactions, radical dimerizations, Michael additions and tributyltin hydride-mediated additions, were investigated by mass spectrometry and the occurring radical cations, carbanions and radicals were detected and characterized as reactive intermediates. The large number of reactions investigated impressively demonstrates the broad applicability of microreactor-coupled ESI-MS for the investigation of chemical reactions in solution.

Pub­lic­a­tions

D. Nauroozi, C. Bruhn, S. Fürmeier, J.-U. Holzhauer, R. Faust
"Microwave-assisted Dibromoolefination of Aromatic and Heteroaromatic Aldehydes and Ketones", J. Heterocycl. Chem2016, 53, 615-619.
DOI: 10.1002/jhet.2332

U. Siemeling, C. Färber, C. Bruhn, S. Fürmeier, T. Schulz, M. Kurlemann, S. Tripp
"Group 10 Metal Complexes of a Ferrocene-Based N-Heterocyclic Carbene: Syntheses, Structures and Catalytic Applications", Eur. J. Inorg. Chem2012, 1413-22. 
DOI: 10.1002/ejic.201100856

S. Fürmeier, Jens Griep-Raming, Ahlke Hayen, J. O. Metzger
"Chelation-controlled Radical Chain Reactions Studied by Electrospray Ionization Mass Spectrometry", Chem. Eur. J. 2005, 11, 5545-5554.
DOI: 10.1002/chem.200500188

C. Scharf, A. Ditze, K. Schwerdtfeger, S. Fürmeier, T. Bruhn, D. E. Kaufmann, J. C. Namyslo
"Investigation of the Structure of Neodymium-Di(2-Ethylhexyl) Phosphoric Acid Combinations Using Electrospray Ionization and Matrix-Assisted Laser Desorption Mass Spectrometry, and Nuclear Magnetic Resonance Spectroscopy", Met. Mat. Trans. 2005, 36B, 429-436.
DOI: 10.1007/s11663-005-0033-0

S. Fürmeier, J. O. Metzger
"Detection of Transient Radical Cations in Electron Transfer Initiated Diels-Alder Reactions by Electrospray Ionization Mass Spectrometry", J. Am. Chem. Soc. 2004, 126, 14485-14492.
DOI: 10.1021/ja046157z

S. Meyer, J. O. Metzger
"Use of electrospray ionization mass spectrometry for the investigation of radical cation chain reactions in solution: detection of transient radical cations", Anal. Bioanal. Chem. 2003, 377, 7-8, 1108-1114.
DOI: 10.1007/s00216-003-2230-5

 S. Meyer, R. Koch, J. O. Metzger

"Untersuchung von reaktiven Zwischenstufen bei chemischen Reaktionen in Lösung mit Elektrospray-Ionisations-Massenspektrometrie: Radikalkation-Kettenreaktionen", Angew. Chem. 2003, 115, 38, 4848-4851; Angew. Chem. Int. Ed. 2003, 42, 38, 4700-4703.

DOI: 10.1002/ange.200352044      DOI: 10.1002/anie.200352044

A. Lützen, F. Thiemann, S. Meyer

"Synthesis of Tetra(BINOL) Substituted Spirofluorenes", Synthesis2002, 18, 2771-2777.
DOI: 10.1055/s-2002-35997

A. Lützen, M. Hapke, S. Meyer
"Synthesis of Bis(BINOL) substituted 2,2´-Bipyridines and their late Transition Metal Complexes", Synthesis2002, 15, 2289-2295.
DOI: 10.1055/s-2002-34948 

J. Griep-Raming, S. Meyer, T. Bruhn, J. O. Metzger
"Untersuchung von reaktiven Zwischenstufen bei chemischen Reaktionen in Lösung mit Elektrospray-Ionisations-Massenspektrometrie: Radikalkettenreaktionen", Angew. Chem. 2002, 114, 2863-2866; Angew. Chem. Int. Ed. 2002, 41, 2738-2742.
DOI: 10.1002/1521-3757(20020802)114:15<2863::AID-ANGE2863>3.0.CO;2-I
DOI: 10.1002/1521-3773(20020802)41:15<2738::AID-ANIE2738>3.0.CO;2-X