Weitere Publikationen von 1994 - heute
Dubin, M. and Nellen, W.: Characterisation of the Dictyostelium homolog of chromatin binding protein DET1 suggests a conserved pathway regulating cell type specification and developmental plasticity. (Eukaryotic Cell, in press)
Dubin, M, Fuchs, J, Gräf, R., Schubert, I. and Nellen, W (2010): Dynamics of a novel centromeric histone variant CenH3 reveals the evolutionary ancestral timing of centromere biogenesis. Nucleic Acids Res. 38, 7526-7537.
Dubin, M. and Nellen, W. (2010): A versatile set of tagged expression vectors to monitor protein localisation and function in Dictyostelium. Gene 465, 1-8.
Sawarkar, R., Visweswariah, S. S., Nellen, W. and Nanjundiah, V. (2009): Histone deacetylases regulate multicellular development of the social amoeba Dictyostelium discoideum. J. Mol. Biol. 391, 833-848
Prevorovsky, M, Grousl, T., Stanurova, J., Rynes, J., Nellen, W., Puta, F. and Folk, P. (2009): Cbf11 and Cbf12, the fission yeast CSL proteins, play opposing roles in cell adhesion and coordination of cell and nuclear division. Exp. Cell Res. 315, 1533-1547.
Jurkowska, R.Z., Ragozine,S., Ansbach, N., Urbanke, C., Nellen, W., Cheng, X. and Jeltsch, A. (2008): Structure and function of Dnmt3a and Dnmt3/3L nucleoprotein filaments. Nucleic Acids Res. 36(21), 6656-6663.
Jurkowski, T.P., Meusburger, M., Phalke, S., Helm, M., Nellen, W., Reuter, G. and Jeltsch, A. (2008): Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism. Rna, 14, 1663-1670.
Li, H., Chen, Q., Kaller, M., Nellen, W., Gräf, R. and De Lozanne, A. (2008): Dictyostelium Aurora kinase has properties of both Aurora A and Aurora B kinases. Eukaryotic Cell, 7, 894-905.
Popov, C., Bliznakov, S., Boycheva, S., Milinovik, N., Apostolova, M.D., Anspach, N., Hammann, C., Nellen, W., Reithmaier, J.P. and Kulisch, W. (2008): Nanocrystalline diamond/amorphous carbon composite coatings for biomedical applications. Diamond & Related Materials 17 (2008) 882.887
A. Hinas, J. Reimegard, E.G.H. Wagner, W. Nellen, V. Ambros & F. Söderbom (2007): The small RNA repertoire of Dictyostelium discoideum and its regulation by components of the RNAi pathway. Nucleic Acids Res. 35, 6714-26.
M. Kaller, B. Földesi & W. Nellen (2007): Mitotic localisation of protein factors involved in chromosome inheritance in Dictyostelium discoideum. Biological Chemistry, 388, 355-365. (Title page)
Popova, M. Kuhlmann, A. Hinas, F. Söderbom & W. Nellen (2006): HelF, a putative RNA helicase acts as a nuclear suppressor of RNAi but not antisense mediated gene silencing. Nucleic Acids Res., 34, 773-784, doi:10.1093/nar/gkj46
A. Jeltsch, W. Nellen & F. Lyko (2006): Two substrates are better than one: dual specificities for Dnmt2 methyltransferases. Trends Biochem Sci, 31, 306-308.
M. Kaller, U. Euteneuer & W. Nellen (2006): Non-redundant HP1-like proteins in Dictyostelium discoideum: different functions during vegetative growth. Eukaryotic Cell 5, 530-543.
W. Nellen (2006): Scanning force microscopy, scanning force spectroscopy. In: Nucleic Acids from A to Z. Edt.: S. Müller, Wiley-VCH, (in press)
R. Chubb, G. Bloomfield, Q. Xu, M. Kaller, A. Ivens, J. Skeöton, B. Turner, W. Nellen, G. Shaulsky, R. R. Kay, W. A. Bickmore, R. H. Singer (2006): Developmental Timing in Dictyostelium is Regulated by the Set1 Histone Methyltransferase. Developmental Biology, 292, 519-532.
M. Kuhlmann, B. Popova & W. Nellen (2006): RNA interference and antisense mediated gene silencing in Dictyostelium. In: Dictyostelium discoideum. Methods in Molecular Biology. Edts.: L. Eichinger and F. Rivera. Humana Press.
M. Kaller, W. Nellen & J. R. Chubb (2006): Chromatin Analysis and Epigenetics. In: Dictyostelium discoideum. Methods in Molecular Biology. Edts.: L. Eichinger and F. Rivera. Humana Press.
Kuhlmann, B. E. Borisova, M. Kaller, P. Larsson, D. Stach, J. Na, L. Eichinger, F. Lyko, V. Ambros, F. Söderbom, C. Hammann and W. Nellen (2005): Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi. Nucleic Acids Res. 33, 6405–6417,
doi:10.1093/nar/gki952M. Kuhlmann, B. Popova & W. Nellen (2005): RNA interference and antisense mediated gene silencing. In: Small RNAs: Analysis and Regulatory Functions. Series “Nucleic Acids and Molecular Biology”, Vol. 17, Edts.: W. Nellen and C. Hammann, Springer, ISBN: 3-540-28129-0
R. Przybilski, S. Gräf, A. Lescoute-Phillips, E. Westhof, W. Nellen, G. Steger, C. Hammann (2005): Hammerhead ribozymes encoded in the genome of A. thaliana. Plant Cell 17, 1877-1885.
T. Brodegger, A. Stockmann, J. Oberstraß, W. Nellen, and H. Follmann (2004): Novel thioredoxin targets in Dictyostelium discoideum identified by two-hybrid analysis. Interactions of thioredoxin with elongation factor 1α and yeast alcohol dehydrogenase. Biological Chemistry, 385, 1185-1192.
W. Nellen (2004): Scanning Force Microscopy and Scanning Force Spectroscopy of RNA. In: Handbook of Biochemistry, Wiley Publishers, Roland Hartmann , Albrecht Bindereif , Astrid Schön , Eric Westhof (Edts.), ISBN: 3-527-30826-1
Gräf S, Borisova BE, Nellen W, Steger G & Hammann C (2004). A database search for double-strand containing RNAs in Dictyostelium discoideum. Biological Chemistry, 385, 961-965
Kuhlmann, M. and Nellen, W. (2004)
RNA-Interferenz. BIUZ 3/2004, 142-150Hammann, C. and Nellen, W. (2003).
RNA: Two in one. Angew Chem Int Ed Eng 42, 714.Nellen, W. and Maniak, M. (2003): Dictyostelium: Cell culture and molecular tools.
Encyclopedia of Life Sciences. Nature Publishing Group., www.els.netY. Klaue, A. Källmann, M. Bonin, W. Nellen & M. Öhman (2003): Biochemical analysis and scanning force microscopy reveal productive and non-productive binding of ADAR2 to RNA substrates. RNA 9, 839-846
S. Funamoto, C. Anjard, W. Nellen & H. Ochiai (2003): cAMP dependent protein kinase regulates
Polyspondylium pallidum development. Differentiation 71, 51-61.H. Martens und W. Nellen.
Genesilencing durch RNAi und antisense RNA.
(2002) Biospektrum 4, 351-354.M. Bonin, R. Zhu, Y. Klaue, J. Oberstrass & W. Nellen (2002):
Analysis of RNA-RNA interaction by scanning force microscopy.
(Nucleic Acids Res., 30, No. 16 e81)J. Oberstraß, M. Bonin, Y. Klaue und W. Nellen:
Rasterkraftmikroskopie: eine neue Sichtweise molekularer Wechselwirkungen.
(Bioforum (2002). 3/2002, 94-96)H. Martens, J. Novotny, J. Oberstrass, T.L. Steck, P. Postlethwait & W. Nellen (2002):
RNAi in Dictyostelium: the role of RdRPs and dsRNase.
(Mol. Biol. Cell, 13, 445-453 (2002).
Full text available at: www.molbiolcell.org/content/vol13/issue2/J. Novotny, S. Diegel, H. Schirmacher, A. Möhrle, M. Hildebrandt, J. Oberstrass & W. Nellen:
Dictyostelium double stranded Ribonuclease.
(Methods in Enzymology, 342, 193-211, 2001)M. Bonin, J. Oberstrass, U. Vogt, M. Wassenegger & W. Nellen:
Binding of IRE-BP to its cognate RNA sequence: SFM studies on a universal RNA backbone
for the analysis of RNA-protein interaction.
(Biol. Chem. 382, 1157-1162, 2001)
www.deGruyter.de/journals/bc/abs/5800.htmlC. Zeng, C. Anjard, G. Primpke, B. Wetterauer, S. Wille & W. Nellen:
Interactin of gdt1 and proteinkinase A (PKA) in the growth-differentiation-transition in Dictyostelium.
(Differentiation 67, 25-32, 2000)Wagner, E.G.H., Altuvia, S. & W. Nellen:
Regulatory RNA.
(Encyclopedia of Life Sciences, 2000, Macmillan Reference Ltd.: www.els.net)M. Bonin, J. Oberstrass, Noemi Lukacs, K. Ewert, E. Oesterschulze, R. Kassing & W. Nellen:
Determination of Preferential Binding Sites for anti-dsRNA Antibodies on Double Stranded RNA by Scanning Force Microscopy.
(RNA 6, 563-570, 2000.)C. Zeng, C. Anjard, K. Riemann, A. Konzok and W. Nellen:
gdt1, a new signal transduction component for negative regulation of the growth-differentiation-transition in Dictyostelium discoideum.
(Molecular Biology of the Cell 11, 1631-1643, 2000)G. Primpke, V. Iassonidou, W. Nellen & B. Wetterauer:
The role of cAMP dependent protein kinase in regulating the initiation of development of Dictyostelium discoideum.
(Developm. Biol. 221, 101-111, 2000)Anjard, C., Chang, W. T. Gross, J. and W. Nellen:
Production and activity of spore differentiation factors (SDFs) in Dictyostelium.
(Development 125, 4067-4075, 1998)C. Anjard, C. Zeng, W.F. Loomis & W. Nellen:
Signal transduction pathways leading to spore differentiation in Dictyostelium discoideum.
(Devlp. Biol. 193(2), pp 146-155, 1998)Zeng, Changjiang:
Molecular Analysis of the Growth-Differentiation-Transitition in Dictyostelium.
Thesis, Kassel-University-Press (1998)P. Oberosler & W. Nellen:
Functional activity and developmental regulation of DdRBP1, a RNA binding protein in Dictyostelium discoideum.
(Biol. Chem. 378, pp 1353-1360, 1997)W. Nellen & C.P. Lichtenstein
Evaluation of antisense effects.
(in: Antisense Technology, A Practical Approach
IRL Press, Oxford, New York, Tokyo,
ISBN 0 19 963584 6, pp 25-38, 1997)C.P. Lichtenstein & W. Nellen (editors):
Antisense technology, A Practical Approach
(IRL Press, Oxford, New York, Tokyo, ISBN 0 19 963584 6, 1997)J. Oberstaß & W. Nellen:
Regulating Genes with Antisense RNA
(in: Antisense Oligodeoxynucleotides and Antisense RNA. Novel Pharmacological and Therapeutic Agents
B. Weiss, Edt., CRC Press, Boca Raton, New York, pp 171-195, 1997)Hildebrandt, M. & Nellen, W.:
Effects of endogenous antisense RNA on RNA stability and translation in Dictyostelium. (in: D. Grierson, G. Lycette, G. Tucker, edts., Mechanisms and Applications of Gene Silencing.) pp15-20 Nottingham University Press, Nottingham, UK (1996). ISBN 1-897676-25-5G. Sczakiel & W. Nellen:
In vitro and in vivo action of antisense RNA.
(Molecular Biotechnology 6, 7-15, 1996)I. Endl, A. Konzok & W. Nellen:
Antagonistic function of intracellular and extracellular cAMP on the expression of discoidin genes in Dictyostelium.
(Mol. Biol. Cell 7, 17 - 24, 1996)A. Kuspa, T. Dingermann & W. Nellen:
Analysis of gene function in Dictyostelium.
(Experientia 51, 1116 - 1123, 1995)J. Blusch, S. Alexander & W. Nellen:
Multiple signal transduction pathways regulate discoidin I gene expression in Dictyostelium discoideum.
(Differentiation 58, 253-260, 1995)M. Sadiq, M. Hildebrandt, M. Maniak & W. Nellen:
Developmental regulation of antisense mediated gene silencing in Dictyostelium.
(Antisense Res. & Development 4, 263-267, 1994)B. Mahal & W. Nellen:
Developmental regulation of DEAD-box proteins and cloning of putative RNA helicase genes from Dictyostelium.
(Biol. Chem. Hoppe Seyler 375, 759-763, 1994)J.W.Hawkins & W. Nellen:
Diversification of antisense Research and Development, Review of the Ringberg Meeting, April 1994:
Mechanisms of Antisense-mediated Gene Silencing.
(Antisense Res. & Development 4, 127-129, 1994)J. Matousek, L. Trnena, R. Oberhauser, C.P. Lichtenstein, & W. Nellen:
dsRNA degrading nucleases are differentially expressed in tobacco anthers.
(Biol. Chem. Hoppe-Seyler, 375, 261-269, 1994)J. Blusch & W. Nellen:
Folate responsiveness during growth and development in Dictyostelium: separate but related pathways control chemotaxis and gene regulation.
(Mol. Microbiol. 11, 331-335, 1994)