Proteins involved in endocytic transit (Aip 1)

Api 1 Text

Top: Actin interacting protein 1 (Aip1, orange dots) on nascent endosomes.

Right: Aip 1-GFP expressing cell during phagocytosis of a yeast particle.

Aip 1 Text 2

Function: Cells with a targeted disruption of Aip 1 are reduced in phagocytosis and macropinocytosis.

Reference:

Konzok at al., 1999

  • Konzok, A., Weber, I., Simmeth, E., Hacker, U., Maniak, M. & Müller-Taubenberger, A.: DAip1, a Dicytostelium homologue of the yeast actin-interacting protein Aip1, is involved in endocytosis, cytokinesis and motility. J. Cell Biol. 146, 453-464, 1999.

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